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  • A complex of C9ORF72 and p62 uses arginine methylation to

     · Together, while C9ORF72 may also have effects on stress granules independent of p62, this suggests that C9ORF72 and p62 form a complex that docks on stress granules

  • Mitochondrial RNA granules are fluid condensates

     · Mitochondria contain the genetic information and expression machinery to produce essential respiratory chain proteins. Within the mitochondrial matrix, newly synthesised RNA, RNA processing proteins, and mitoribosome assembly factors form punctate sub-compartments referred to as mitochondrial RNA granules (MRGs) 1–3.Despite their proposed importance in regulating gene

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